Publications
  1. Stephenson, G., Stowell, J., Toma, P., Dorman, D., Greeene, J., Byrn, S. “Solid-State Analysis of Polymorphic, Isomorphic, and Solvated Forms of Dirithromycin,” J. Am. Chem. Soc. 1994, 116, 5766-5773.
  2. Byrn, S., Pfeiffer, R., Stephenson, G., Grant, D., and Gleason, W. “Solid-State Pharmaceutical Chemistry,” Chemistry of Materials. 1994,6,1148-1158.
  3. Stephenson, G., Borchardt, T., Byrn, S., Bowyer, J., Bunnell, C., Snorek, S., Yu, L. “Conformational and Color Polymorphism of 5-Methyl-2-[(2-nitrophenyl)amino]-3- thiophenecarbonitrile,” J. Pharm. Sci., 1995, 84(11), 1385-1386.
  4. Stephenson, G., Wozniak, T., Stowell, J., and Byrn, S. “Nizatidine, N-[2-[[[2-[(dimethylamino)methyl]-4-thiazolyl]methyl]thio]ethyl]-N’-methyl-2-nitro-1, 1-ethenediamine,” J. Mol. Struct. 1996, 380, 93-100.
  5. Wirth, D., Stephenson, G., “Purification of Dirithromycin. Impurity Reduction and Polymorphic Manipulation,” Org. Proc. Res. and Dev. 1997, 1, 55-60.
  6. Stephenson, G., Pfeiffer, R., and Byrn, S. “Solid-state investigation of the tautomerism of acetohexamide,” Int. J. Pharm. 1997, 146, 93-99.
  7. Baertschi, S., Dorman, D., Occolowitz, J., Collins, M., Spangle, L., Stephenson, G., and Lorenz, L. “Isolation and Structure Elucidation of the Major Degradation Products of Cefaclor Formed Under Aqueous Acidic Conditions,” J. Pharm. Sci. 1997, 86, 526-539.
  8. Stephenson, G., Stowell, J., Toma, P., and Byrn, S. “Solid-State Investigations of Erythromycin A Dihydrate: Structure, NMR Spectroscopy, and Hygroscopicity,” Pharm. Sci., 86(11), 1239-1244, 1997.
  9. Benovsky P., Stephenson, G., Stille, J.R. “Asymmetric Formation of Quaternary Centers through Aza-Annulation of Chiral β-Enamino Amides with Acrylate Derivatives,” Journal of the American Chemical Society.120(11), 1998, 2493-2500.
  10. Stephenson, G., Groleau, E., Kleeemann, R., Xu, W., and Rigsbee, D. “Formation of Isomorphic Desolvates: Creating a Molecular Vacuum,” J. Pharm. Sci., 87(5), 536-542, 1998.
  11. Yu, L.; Reutzel, S.M.; Stephenson, G.A. “Physical characterization of polymorphic drugs: an integrated characterization strategy”, Pharmaceutical Science and Technology Today, 1(3), 1998.118-126.
  12. Goekjian, Peter G.; Saebo, Svein; Gillig, James R.; Stephenson, Gregory A.; Dale, Christopher B.; Blankenbiller, Dani L.; Dudley, Tamara P. The effect of the macrocycle on the conformation of the bis(indolyl)maleimide of LY333531 and related compounds. 216th ACS National Meeting, Boston, August 23-27, 1998.
  13. Schmid, C. R.; Glasebrook, A. L..; Misner, J. W.; Stephenson, G. A. “Synthesis and Biological Activity of trans-2,3-Dihydroraloxifene” Bioorg. Med. Chem. Lett. , 9, 1137-1140, 1999.
  14. Lian Yu, Gregory A. Stephenson, Christine A. Mitchell, Charles A. Bunnell, Sharon V. Snorek, J. Joe Bowyer, Thomas B. Borchardt,, Joseph G. Stowell, and Stephen R. Byrn Thermochemistry and Conformational Polymorphism of a Hexamorphic Crystal System. J. Am. Chem. Soc., 4, 585-591, 2000.
  15. Stephenson G.A. and Diseroad, B.A. Structural Relationship and Desolvation Behavior of Cromolyn, Cefazolin and Fenoprofen Sodium Hydrates Int. J. Pharm., 198(2), 167-177, 2000.
  16. Stephenson G.A. Diseroad, B.A., and Farb, P. Structure Determination from Conventional Powder Diffraction Data: Application to Hydrates, Hydrochloride Salts and Metastable Polymorphs. J. Pharm. Sci., 89(7), 958-966, (2000).
  17. Escribano, A., Pedregal. C, Gonzalez, R., Fernandez, A., Burton, K., Stephenson, G.A. Diastereoselective Cyclopropanation of cyclic enones with methyl dichloroacetate anion. Tetrahedron, 57(46), 9423-9427, 2001.
  18. Stephenson, G.A., Forbes, R.A., Reutzel-Edens, S.M. Characterization of the Solid-State: Quantitative Issues Advanced Drug Delivery Reviews, 48(1) 67-90, 2001.
  19. Borghese, A., Luc, Antoine, L., Stephenson, G.A. Novel Chemoselective Reduction of the Tetrahydro-4-pyridyl Versus Indole Moiety Governed by Electorn Donation: First X-ray Evidence for Indolopiperidyl-borane Complexation Chemical Process Research and Development, 43(45), 8087-8090, 2002.
  20. Scarlett, N.V.Y., Madsen, I.C., Cranswick, L.M.D., Lwin, T., Groleau, E. Stephenson, G., Aylmore, M., Agron-Olshina, N. Outcomes of the International Union of Crystallographic Commission on Powder Diffraction Round Robin on Quantitative Phase Analysis: samples 2,3,4,synthetic bauxite, natural grandiorite and pharmaceuticals. Journal of Applied Crystallography, 35(4) 383-400, 2002.
  21. Shepherd, T.A., Aikens, J.A., Bleakman, D., Cantrell, B.E., Rearick, J.P., Simon, R.L., Edward, C.R., Stephenson, G.A., Zimmerman, D.M., Mandelzys, A., Jarvie, K.R., Ho, K., Deverill, M, Kamboj, R.K. Design and Synthesis of a Novel Series of 1,2-Disubstituted Cyclopentanes as Small, Potent Potentiatiors of 2-Amino-3-(3-hydroxy-5-methyl-isoxazol-4-yl)propanoic Acid (AMPA) Receptors Journal of Medicinal Chemistry, 45(10) 2101-2111, 2002.
  22. Reutzel-Edens, Susan M.; Bush, Julie K.; Stephenson, Gregory A.. Engineering crystals of pharmaceutical solids Abstracts of Papers, Abstract; 223rd ACS National Meeting, Orlando, FL, United States, April 7-11, 2002.
  23. Stephenson, G.A., and Young, R. Potential Application of Rietveld Analysis in the Pharmaceutical Industry. American Pharmaceutical Review, 4(4) 46-51, 2002.
  24. Reutzel-Edens, Susan M.; Bush, Julie K.; Magee, Paula A.; Stephenson, Greg A.; Byrn, Stephen R. Anhydrates and Hydrates of Olanzapine: Crystallization, Solid-State Characterization, and Structural Relationships. Crystal Growth & Design, 3(6), 897-907, 2003.
  25. Xu, Yanping; Rito, Christopher J.; Etgen, Garret J.; Ardecky, Robert J.; Bean, James S.; Bensch, William R.; Bosley, Jacob R.; Broderick, Carol L.; Brooks, Dawn A.; Dominianni, Samuel J.; Hahn, Patric J.; Liu, Sha; Mais, Dale E.; Montrose-Rafizadeh, Chahrzad; Ogilvie, Kathy M.; Oldham, Brian A.; Peters, Mary; Rungta, Deepa K.; Shuker, Anthony J.; Stephenson, Gregory A.; Tripp, Allie E.; Wilson, Sarah B.; Winneroski, Leonard L.; Zink, Richard; Kauffman, Raymond F.; McCarthy, James R. Design and Synthesis of α-Aryloxy-α-methylhydrocinnamic Acids: A Novel Class of Dual Peroxisome Proliferator-Activated Receptor α/γ Agonists. Journal of Medicinal Chemistry, 47(10), 2422-2425, 2004.
  26. Yan, Jiangli; Delaglio, Frank; Kaerner, Andreas; Kline, Allen D.; Mo, Huaping; Shapiro, Michael J.; Smitka, Tim A.; Stephenson, Gregory A.; Zartler, Edward R. Complete Relative Stereochemistry of Multiple Stereocenters Using Only Residual Dipolar Couplings. Journal of the American Chemical Society, 126(15), 5008-5017, 2004.
  27. Magnus, Nicholas A.; Aikins, James A.; Cronin, Jason S.; Diseroad, William D.; Hargis, Amy D.; LeTourneau, Michael E.; Parker, Bruce E.; Reutzel-Edens, Susan M.; Schafer, John P.; Staszak, Michael A.; Stephenson, Gregory A.; Tameze, Shella L.; Zollars, Lisa M. H. Diastereomeric Salt Resolution Based Synthesis of LY503430, an AMPA (α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid) Potentiator. Org. Proc. Res. & Dev., (2005) 9(5), 621-628.
  28. Stephenson, Gregory A.; Khan, M. Amin; Maple, Steven R. High Throughput Salt and Polymorph Screening of Pharmaceuticals. Abstract; 36th Central Regional Meeting of the ACS, Indianapolis, IN, United States, June 2-4 (2004).
  29. Stephenson, Gregory A. Applications of X-ray powder diffraction in the pharmaceutical industry. Rigaku Journal (2005), 22(1), 2-15.
  30. Aikins, James A.; Haurez, Michael; Rizzo, John R.; Van Hoeck, Jean-Pierre; Brione, Willy; Kestemont, Jean-Paul; Stevens, Christophe; Lemair, Xavier; Stephenson, Gregory A.; Marlot, Eric; Forst, Mindy; Houpis, Ioannis N. Synthesis of a Peroxime Proliferator Activated Receptor (PPAR) Agonist via Stereocontrolled Williamson Ether Synthesis and Stereospecific SN2 Reaction of S-2-Chloro Propionic Acid with Phenoxides. Journal of Organic Chemistry (2005), 70(12)
  31. Bradley L Ackermann; Ajai K Chaudhary; Gurkeerat Singh; Gregory A Stephenson Book Chapter in “Remington: The Science and Practice of Pharmacy”, 21st Edition
  32. Parthasarathy, Saravanan; Fernandez, Maria-Carmen; Mateo, Ana I.; Escribano, Ana; Martin de la Nava, Eva M.; Wang, Xiaodong; Cockerham, Sandra L.; Beyer, Thomas P.; Schmidt, Robert J.; Cao, Guoging; Stephenson, Gregory; Mantlo, Nathan B. Tetrahydro naphthyridine as inhibitors of cholesteryl ester transfer protein Discovery Chemistry Research & Technology, Eli Lilly and Company, Indianapolis, IN, USA. Abstract; 232nd ACS National Meeting, San Francisco, CA, United States, Sept. 10-14, 2006 (2006).
  33. Stephenson, G.A. Anisotropic Lattice Contraction in Pharmaceuticals: The Influence of Cryo-crystallography on Calculated Powder Diffraction Patterns J. Pharm. Sci. (2006), 47(17), 821-827.
  34. Masquelin, Thierry; Bui, Hai; Brickley, Bob; Stephenson, Gregory; Schwerkoske, John; Hulme, Christopher. Sequential Ugi/Strecker reactions via microwave assisted organic synthesis: novel 3-center-4-component and 3-center-5-component multi-component reactions. Tetrahedron Letters (2006), 47(17), 2989-2991.
  35. Magnus, Nicholas A.; Aikins, James A.; Cronin, Jason S.; Diseroad, William D.; Hargis, Amy D.; LeTourneau, Michael E.; Parker, Bruce E.; Reutzel-Edens, Susan M.; Schafer, John P.; Staszak, Michael A.; Stephenson, Gregory A.; Tameze, Shella L.; Zollars, Lisa M. H. Diastereomeric Salt Resolution Based Synthesis of LY503430, an AMPA (α -Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid) Potentiator. Organic Process Research & Development (2005), 9(5), 621-628.
  36. Chaudhary, A.K., Gurkeerat S., Stephenson, Gregory A., Ackermann, B.L. Instrumental Methods of Analysis in Remmington: The Science and Practice of Pharmacy (2006) 633-671.
  37. Yu, Ying, Stephenson, Gregory A., Mitchell, D. A regioselective synthesis of 3-benzazepinones via Intramolecular Hydroamidation of Acetylenes. Tetrahedron Letters (2006) 47(23), 3811-3814.
  38. Stephenson, G. A. and Cikui Liang.; Structural Determination of the Stable and Metastable forms of Atomoxetine HCl using Single Crystal and Powder X-ray Diffraction Methods” Journal of Pharmaceutical Sciences. (2006) 95(8), 1677-1683.
  39. Victor, Frantz; Zhang, Deyi; Bender, David M.; Peterson, Jeffrey A.; Boyer, Robert D.; Stephenson, Gregory A.; Azman, Adam; McCarthy, James R. Conversion of N4-(α-aminoacyl)cytidines to N-(4-cytidinyl)amino acid amides by a novel rearrangement reaction. Abstract; 232nd ACS National Meeting, San Francisco, CA, United States, Sept. 10-14, 2006 (2006).
  40. Carballares, Santiago; Cifuentes, Marta M.; Stephenson, Gregory A. Regioselective two step synthesis of 3-substituted 2-aminoimidazo[1,2-a]pyrimidines. Tetrahedron Letters (2007), 48(11), 2041-2045.
  41. Monn, James A.; Massey, Steven M.; Valli, Matthew J.; Henry, Steven S.; Stephenson, Gregory A.; Bures, Mark; Herin, Marc; Catlow, John; Giera, Deborah; Wright, Rebecca A.; Johnson, Bryan G.; Andis, Sherri L.; Kingston, Ann; Schoepp, Darryle D. Synthesis and Metabotropic Glutamate Receptor Activity of S-Oxidized Variants of (-)-4-Amino-2-thiabicyclo-[3.1.0]hexane-4,6-dicarboxylate: Identification of Potent, Selective, and Orally Bioavailable Agonists for mGlu2/3 Receptors. Journal of Medicinal Chemistry (2007), 50(2), 233-240.
  42. Bell, Michael; Gernert, Douglas; Grese, Timothy; Belvo, Matthew; Borromeo, Peter; Kelley, Sally; Kennedy, Joseph; Kolis, Stanley; Lander, Peter; Richey, Rachel; Sharp, Scott; Stephenson, Gregory; Williams, Jeffrey; Yu, Hannah; Zimmerman, Karen; Jadhav. (S)-N-{3-[1-Cyclopropyl-1-(2,4-difluoro-phenyl)-ethyl]-1H-indol-7-yl}-methanesulfonamide: A Potent, Non Steroidal, Functional Antagonist of the Mineralocorticoid Receptor. Journal of Medicinal Chemistry (2007), 50(26), 6443-6445.
  43. Zhang, Deyi; Bender, David M.; Victor, Frantz; Peterson, Jeffrey A.; Boyer, Robert D.; Stephenson, Gregory A.; Azman, Adam; McCarthy, James R. Facile rearrangement of N4-(-aminoacyl)cytidines to N-(4-cytidinyl)amino acid amides. Tetrahedron Letters (2008), 49(13), 2052-2055.
  44. Bender, David M.; Bao, Jingqi; Dantzig, Anne H.; Diseroad, William D.; Law, Kevin L.; Magnus, Nicholas A.; Peterson, Jeffrey A.; Perkins, Everett J.; Pu, Yangwei J.; Reutzel-Edens, Susan M.; Remick, David M.; Starling, James J.; Stephenson, Gregory A.; Vaid, Radhe K.; Zhang, Deyi; McCarthy, James R. Synthesis, Crystallization, and Biological Evaluation of an Orally Active Prodrug of Gemcitabine. Journal of Medicinal Chemistry (2009), 52(22), 6958-6961.
  45. Kopach, Michael E.; Singh, Utpal K.; Kobierski, Michael E.; Trankle, William G.; Murray, Michael M.; Pietz, Mark A.; Forst, Mindy B.; Stephenson, Gregory A.; Mancuso, Vincent; Giard, Thierry; Vanmarsenille, Michel; De France, Thierry. Practical Synthesis of Chiral 2-Morpholine: (4-Benzylmorpholin-2-(S)-yl)-(tetrahydropyran-4-yl) methanone Mesylate, a Useful Pharmaceutical Intermediate. Organic Process Research & Development (2009), 13(2), 209-224.
  46. Stephenson, G.A. Analysis of physical transformation of API during manufacture and storage. From Formulation and Analytical Development for Low-Dose Oral Drug Products Ed. Jack Zheng (2009), 283-308.
  47. Bender, David M.; Bao, Jingqi; Dantzig, Anne H.; Diseroad, William D.; Law, Kevin L.; Magnus, Nicholas A.; Peterson, Jeffrey A.; Perkins, Everett J.; Pu, Yangwei J.; Reutzel-Edens, Susan M.; Remick, David M.; Starling, James J.; Stephenson, Gregory A.; Vaid, Radhe K.; Zhang, Deyi; McCarthy, James R. Synthesis, Crystallization, and Biological Evaluation of an Orally Active Prodrug of Gemcitabine. Journal of Medicinal Chemistry (2009), 52(22), 6958-6961.
  48. Reutzel-Edens, S.R., Stephenson, G.A., Solid-State pharmaceutical development: Ensuring stability through salt and polymorph screening in Pharmaceutical Stress Testing, Predicting Drug Degradation Editors Baertschi, S.W., Alsante, K.M., Reed, R.A. (2011) 254-285.
  49. Stephenson, Gregory A.; Aburub, Aktham; Woods, Timothy A. Physical stability of salts of weak bases in the solid-state. Journal of Pharmaceutical Sciences (2011), 100(5), 1607-1617.
  50. Fernandez, M.C.; Escribano, A.; Mateo, A.I.; Parthasarathy, S.; de la Nava, M., E. M.; Wang, X..; Cockerham, S.L.; Beyer, T.P.; Schmidt, R. J.; Cao, G.; Zhang, Y.; Jones, T.M.; Borel, A.; Sweetana, S.A.; Cannady, E.A.; Stephenson, G.; Frank, S.; Mantlo, N.B. Design, synthesis and structure-activity-relationship of 1,5-tetrahydronaphthyridines as CETP inhibitors. Bioorganic & Medicinal Chemistry Letters (2012), 22(9), 3056-3062.
  51. Stephenson, Gregory A.; Kendrick, John; Wolfangel, Craig; Leusen, Frank J. J. Symmetry Breaking: Polymorphic Form Selection by Enantiomers of the Melatonin Agonist and Its Missing Polymorph. Crystal Growth & Design (2012), 12(8), 3964-3976.
  52. Magnus, Nicholas A.; Astleford, Bret A.; Laird, Dana L.; Rizzo, John R.; Ruble, J. C.; Stephenson, Gregory A.; Wepsiec, James P. Syntheses of serotonin norepinephrine reuptake inhibitors (SNRIs): From resolutions to dynamic kinetic resolution/enantioselective hydrogenation. Abstract; 245th ACS National Meeting & Exposition, New Orleans, LA, United States, April 7-11, 2013 (2013)
  53. Merritt, Jeremy M.; Viswanath, Shekhar K.; Stephenson, Gregory A.. Implementing Quality by Design in Pharmaceutical Salt Selection: A Modeling Approach to Understanding Disproportionation. Pharmaceutical Research (2013), 30(1), 203-217.
  54. Kendrick, J.; Stephenson, G. A.; Neumann, M. A.; Leusen, F. J. J. Crystal structure prediction of a flexible molecule of pharmaceutical interest with unusual polymorphic behavior. Crystal Growth & Design (2013), 13, 581−589.
  55. Magnus, N.A., Astleford, B.A., Laird, D.L.T., Maloney, T.D., McFarland, A.D., Rizzo, J.R., Ruble, J.C., Stephenson, G.A., Wepsiec, J.P. Additives Promote Noyori-type Reductions of a β-Keto-γ-lactam: Asymmetric Syntheses of Serotonin Norepinephrine Reuptake Inhibitors Journal of Organic Chemistry (2013), 78(11), 5768-5774.
  56. Monn, J.A.; Valli, M.J.; Massey, S.M.; Hao, J.; Reinhard, M.R.; Bures, M.G.; Heinz, B.A.; Wang, X.S; Carter, J.H.; Getman, B.G.; Stephenson , G.A.; Herin, M.; Catlow, J.T.; Swanson, S.; Johnson, B.G.; McKinzie, D.L. and Henry, S.S. Synthesis and Pharmacological Characterization of 4-Substituted-2-Aminobicyclo[3.1.0]hexane-2,6-Dicarboxylates: Identification of New Potent and Selective Metabotropic Glutamate 2/3 Receptor Agonists. Journal of Medicinal Chemistry (2013), 56(11), 4442-4455.
  57. Dreyfus, N., Myers, J.K., Badescu, V.O., de Frutos, O., de la Puente, M.L., Ding, C., Filla, S.A. Fynboe, K., Gernert, D.L. Heinz, B.A., Hemrick-Luecke, S.K., Johnson, K.W.; Johnson, M.P.; López, P.; Love, P.L.; Martin, L.J.; Masquelin, T.; McCoy, M.J.; Mendiola, J.; Morrow, D.; Muhlhauser, M.; Pascual, G.; Perun, T.J.; Pfeifer, L.A.; Phebus, L.A.; Richards, S.J.; Rincón, J.A.; Seest, E.P.; Shah, J.; Shaojuan, J.; Simmons, R.M.A.; Stephenson, G.A.; Tromiczak, E.G.; Thompson, L.K.; Walter, M.W.; Weber, W.W.; Zarrinmayeh, H.; Thomas, C.E.; Iyengar, S. and Johansson, A. Discovery of a Potent, Dual Serotonin and Norepinephrine Reuptake Inhibitor. ACS Medicinal Chemistry Letters (2013), 4(6), 560-564.
  58. Stephenson, G.A. Symmetry breaking in crystallizations: Different polymorphic selection by R- and Senantiomers in achiral media (missing polymorph of the melatonin agonist). Abstract; 246th ACS National Meeting & Exposition, Indianapolis, IN, United States, September 8-12, 2013 (2013).
  59. Syntheses of serotonin norepinephrine reuptake inhibitors (SNRIs): From resolutions to dynamic kinetic resolution/enantioselective hydrogenation Magnus, Nicholas A.; Astleford, Bret A.; Laird, Dana L.; Rizzo, John R.; Ruble, J. C.; Stephenson, Gregory A.; Wepsiec, James P. Abstract; 245th ACS National Meeting & Exposition, New Orleans, LA, United States, April 7-11, 2013 (2013), ORGN-345.
  60. Kissane, M.G.; Frank, S.A.; Rener, G.A.; Ley, C.P.; Alt, C.A.; Stroud, P.A.; Vaid, R.K.; Boini, S.K.; McKee, L.A.; Vicenzi, J.T.; Stephenson, G.A. Counterion effects in the preparation of aldehyde-bisulfite adducts. Tetrahedron Letters (2013), 54 (48), 6587-6591.
  61. Baertschi, S.;Jansen, P.; Montgomery, R.; Smith, W.;Draper, J.; Myers, D.; Houghton, P.; Sharp, V.; Guisbert,A.;Zhuang, H.; Watkins, M.; Stephenson, G. Investigation of the Mechanism of Racemization of Litronesib in Aqueous Solution: Unexpected Base-Catalyzed Inversion of a Fully Substituted Carbon Chiral Center. Journal of Pharmaceutical Science (2014), 103(9), 2797-2808.
  62. Alsante,K.M.;Baertschi,S.W.;Reed,R.A.;Landis,M.S.;Furness,S.;Olsen,B.;Mowery,M.;Russo,K.;Iser,R.; Stephenson,G.A.;Jansen, P. Recent Trends in Product Development and Regulatory Issues on Impurities in Active Pharmaceutical Ingredient (API) and Drug Products. Part 2: Safety Considerations of Impurities in Pharmaceutical Products and Surveying the Impurity Landscape. AAPS PharmSciTech (2013), p1-13.
  63. Thakral, N.K., Mohapatra, S. Stephenson, G.A., Suryanarayanan, R. Compression-induced crystallization of amorphous indomethacin in tablets – characterization of spatial heterogeneity by two-dimensional X-ray diffractometry. Molecular Pharmaceutics (2015), 12(1), 253-263.
  64. Almeida e Sousa, L., Reutzel-Edens, S.M., Stephenson, G.A., Taylor, L.S.Assessment of the Amorphous Solubility of a Diverse Group of Drugs Using New Experimental and Theoretical Approaches. Molecular Pharmaceutics (2015), 12(2), 484-495.
  65. Thakral, N.K., Yamada, H., Stephenson, G.A., Suryanarayanan, R. Spatial Distribution of Trehalose Dihydrate Crystallization in Tablets by X-ray Diffractometry. Molecular Pharmaceutics (2015), 12(10), 3766-3775.
  66. Almeida e Sousa, L., Reutzel-Edens, S.M., Stephenson, G.A., Taylor, L.S. Supersaturation Potential of Salts, Co-Crystals and Amorphous Forms of a Model Weak Base. Crystal Growth & Design (2016), 16(2), 737-748.
  67. Thakral, N.K., Behme, R.J., Aburub, A., Pederson, J.A., Woods, T.A., Diseroad, B.A., Suryarnarayanan, R., Stephenson, G.A. Salt Disproportionation in the Solid State: Role of Solubility and Counterion Volatility. Molecular Pharmaceutics (2016), 13(12), 4145-4151.
  68. Gardinier, K.M., Gernert, D.L., Porter, W.J., Reel, J.K., Ornstein, P.L., Spinazze, P.S., Craig, H., Stephenson, G.A. et al. Discovery of the First α-​Amino-​3-​hydroxy-​5-​methyl-​4-​isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-​8. Journal of Medicinal Chemistry (2016), 59(10), 4753-4768.
Recent Invited Presentations
  1. Columbia University, Department of Material Science and Engineering “Solid-State Pharmaceutical Chemistry” April 27th, 2012.
  2. American Chemical Society (ACS) M3 Conference Molecules, Materials, and Medicines Conference “Symmetry Breaking: Polymorphic Form Selection by Enantiomers of the Melatonin Agonist and Its Missing Polymorph” May 19, 2012.
  3. International Centre for Diffraction PPXRD Conference “Symmetry Breaking: Polymorphic Form Selection by Enantiomers of the Melatonin Agonist and Its Missing Polymorph” May 22, 2012.
  4. University of Wisconsin, Madison. Pharmaceutical Sciences Seminar; “Solid-State Chemistry in Pharmaceutical Development”, Oct. 5, 2012.
  5. American Association of Pharmaceutical Sciences, National Meeting, “Relations of Physical Form Changes to Impurity Formation” October 2012.
  6. Stephenson, G.A. Symmetry breaking in crystallizations: Different polymorphic selection by R- and S- enantiomers in achiral media (missing polymorph of the melatonin agonist). Abstract; 246th ACS National Meeting & Exposition, Indianapolis, IN, United States, September 8-12, 2013 (2013).
  7. Stephenson, G.A. Novel and Emerging Crystallization Technology; “Symmetry Breaking in Crystallization: Different Polymorphic Selection by Opposite Enantiomers in Achiral Media”; Association for Crystallization Technology 19th Larson Workshop, Indianapolis, IN Oct. 7, 2013.
  8. Stephenson, G.A. David Grant Symposium, “Salt screening and Selection of Pharmaceuticals,” University of Minnesota, May 20-22, 2014.